Decreased levels of endocannabinois in glaucoma
The endocannabinoids anandamide, 2-AG (2- arachidonoylglycerol) and PEA (palmitylethanolamide) are present in several ocular tissues, including cornea, iris, ciliary body and retina. New research demonstrated that in eyes from patients with glaucoma, significantly decreased levels of 2-AG and PEA are present in the ciliary body. Since the ciliary body is an important tissue in the regulation of intraocular pressure these findings suggest that these endocannabinoids may have a role in glaucoma.
(Source: Chen J, et al. Biochem Biophys Res Commun 2005;330(4):1062-7)
